Prescription onlySexual Health — Men · Prescription
Tadalafil + Sildenafil
Tadalafil 20mg · Sildenafil 70mg
Two PDE5 ingredients in one tablet — fast onset plus a long window.
From $145 · 6 doses
You're only charged if a provider prescribes.
What is Tadalafil + Sildenafil?
Tadalafil 20mg and sildenafil 70mg in one rapid-dissolve tablet — combining the quicker start of sildenafil with the longer window of tadalafil.
What's included
Your prescription, what you need to use it, and written directions from your clinician.
Benefits
- Two proven ingredients
- Quick start, long window
- For when one isn't enough
- One tablet, not two
How it's taken
Rapid-dissolve tablet · as needed. Your clinician writes your schedule after reviewing your assessment.
- Take about 30–60 minutes before activity, dissolved under the tongue or on it.
- No more than one dose in 24 hours unless your provider says otherwise.
- A heavy, high-fat meal can slow how quickly it starts working.
Safety
- Never take with nitrates (nitroglycerin, isosorbide) or riociguat — the combination can cause a dangerous drop in blood pressure.
- Use caution with alpha-blockers and other blood-pressure medications; tell your provider everything you take.
- Common effects include headache, flushing, nasal congestion, indigestion, and dizziness.
- Seek care immediately for an erection lasting more than 4 hours, or any sudden loss of vision or hearing.
- Compounded medications are prepared by state-licensed pharmacies for individual patients. They are not FDA-approved, and the FDA does not verify their safety, effectiveness, or quality.
Benefits
Tadalafil + Sildenafil: fast onset and a long window, together

Two proven ingredients
Sildenafil and tadalafil are the two most widely prescribed ED medications.

Quick start, long window
Sildenafil's faster onset combined with tadalafil's longer duration.

For when one isn't enough
Often considered when a single ingredient hasn't given the response someone wanted.

One tablet, not two
Both ingredients in a single dose that dissolves on your tongue.
How it works
Tadalafil + Sildenafil at a glance

Two ingredients
Both of the most-prescribed ED ingredients in one tablet.
Start and stay
One starts quickly, the other lasts longer.
When one falls short
An option if a single ingredient wasn't enough.
Start your assessment
Step1A short online health questionnaire. No appointment, no waiting room.

A provider reviews it
Step2A clinician licensed in your state reviews your history and prescribes only if it's appropriate.

The pharmacy ships it
Step3A state-licensed U.S. pharmacy fills your prescription and ships it in plain packaging.

Care continues
Step4Message your care team with questions. Dose changes and refills are handled online.

Explore other treatments
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View Sildenafil + Tadalafil + Vardenafil + Apomorphine
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FAQ
Questions, answered
Why combine two PDE5 ingredients?
Is my information private?
Do you take insurance?
Prescription required. All prescriptions require evaluation by a licensed provider, and completing an assessment does not guarantee a prescription.
Plans and renewals. Plans renew monthly at the price shown at checkout until you cancel. You can cancel any time.
This page is not medical advice. Individual results vary.