Prescription onlySexual Health — Men · Prescription
Sildenafil + Pycnogenol
Sildenafil 80mg · Pycnogenol 50mg
Fast-acting sildenafil paired with pycnogenol in a rapid-dissolve tablet.
From $65 · 6 doses
You're only charged if a provider prescribes.
What is Sildenafil + Pycnogenol?
Sildenafil 80mg with pycnogenol 50mg in a rapid-dissolve tablet — the most familiar ED ingredient, with a botanical studied for blood-vessel support.
What's included
Your prescription, what you need to use it, and written directions from your clinician.
Benefits
- The ingredient most men know
- Works within about an hour
- Pycnogenol added
- No water needed
How it's taken
Rapid-dissolve tablet · as needed. Your clinician writes your schedule after reviewing your assessment.
- Take about 30–60 minutes before activity, dissolved under the tongue or on it.
- No more than one dose in 24 hours unless your provider says otherwise.
- A heavy, high-fat meal can slow how quickly it starts working.
Safety
- Never take with nitrates (nitroglycerin, isosorbide) or riociguat — the combination can cause a dangerous drop in blood pressure.
- Use caution with alpha-blockers and other blood-pressure medications; tell your provider everything you take.
- Common effects include headache, flushing, nasal congestion, indigestion, and dizziness.
- Seek care immediately for an erection lasting more than 4 hours, or any sudden loss of vision or hearing.
- Compounded medications are prepared by state-licensed pharmacies for individual patients. They are not FDA-approved, and the FDA does not verify their safety, effectiveness, or quality.
Benefits
Sildenafil + Pycnogenol: fast-acting and familiar

The ingredient most men know
Sildenafil is the active ingredient in the first widely prescribed ED medication.

Works within about an hour
Typically effective for roughly 4–6 hours after it starts working.

Pycnogenol added
A pine-bark extract studied for blood-vessel function, included as a supporting ingredient.

No water needed
Dissolves on or under the tongue.
How it works
Sildenafil + Pycnogenol at a glance

A well-known ingredient
One of the most-studied ED ingredients.
Quick to start
Usually begins working within the hour.
Pycnogenol inside
A pine-bark extract comes in the same tablet.
Start your assessment
Step1A short online health questionnaire. No appointment, no waiting room.

A provider reviews it
Step2A clinician licensed in your state reviews your history and prescribes only if it's appropriate.

The pharmacy ships it
Step3A state-licensed U.S. pharmacy fills your prescription and ships it in plain packaging.

Care continues
Step4Message your care team with questions. Dose changes and refills are handled online.

Explore other treatments
View Tadalafil + Pycnogenol
Starts from $68
View Tadalafil + Sildenafil
Starts from $145
View Daily Tadalafil + Vardenafil Chew
Starts from $90
View Tadalafil + Bremelanotide
Starts from $103
View Sildenafil + Bremelanotide
Starts from $160
View Apomorphine + Sildenafil + Tadalafil
Starts from $103
View Tadalafil + Sildenafil + Apomorphine 4mg
Starts from $115
View Sildenafil + Tadalafil + Vardenafil + Apomorphine
Starts from $119
FAQ
Questions, answered
How is this different from the tadalafil option?
Is my information private?
Do you take insurance?
Prescription required. All prescriptions require evaluation by a licensed provider, and completing an assessment does not guarantee a prescription.
Plans and renewals. Plans renew monthly at the price shown at checkout until you cancel. You can cancel any time.
This page is not medical advice. Individual results vary.